One-Pot Cajun Chicken Alfredo

Featured in: Easy Weeknight Eats

This one-pot meal blends tender chicken pieces with smoky Cajun seasoning, simmered alongside orzo pasta in a rich Alfredo sauce. Aromatic onions, garlic, and bell pepper build a flavorful base, enlivened by smoked paprika and a hint of cayenne pepper. The dish finishes with freshly grated Parmesan cheese and optional baby spinach, creating a silky and satisfying dinner perfect for busy weeknights. Garnish with parsley and extra cheese for added color and taste.

Updated on Sun, 23 Nov 2025 10:56:00 GMT
One-Pot Cajun Chicken Alfredo Orzo, a creamy skillet full of tender chicken and orzo pasta. Save
One-Pot Cajun Chicken Alfredo Orzo, a creamy skillet full of tender chicken and orzo pasta. | tazzsip.com

A creamy, spicy, and comforting one-pot meal combining tender chicken, smoky Cajun spices, velvety Alfredo sauce, and orzo pasta for a quick weeknight dinner.

I first served this to my family on a busy weeknight, and it quickly became a favorite because of its rich flavors and ease of preparation.

Ingredients

  • Proteins: 2 large boneless skinless chicken breasts (about 450 g) cut into bite sized pieces
  • Vegetables: 1 small yellow onion finely chopped, 3 cloves garlic minced, 1 red bell pepper diced, 1 cup baby spinach roughly chopped (optional)
  • Pantry: 2 tablespoons olive oil, 1 1/2 cups (300 g) orzo pasta, 2 1/2 cups (600 ml) low sodium chicken broth, 1 cup (240 ml) heavy cream, 1/2 cup (120 ml) milk
  • Spices & Seasonings: 1 tablespoon Cajun seasoning (store bought or homemade), 1/2 teaspoon smoked paprika, 1/2 teaspoon salt or to taste, 1/4 teaspoon freshly ground black pepper, pinch of cayenne pepper (optional for extra heat)
  • Cheeses: 3/4 cup (75 g) freshly grated Parmesan cheese
  • Garnish: Chopped fresh parsley, Extra Parmesan cheese

Instructions

Step 1:
Season the chicken pieces with half of the Cajun seasoning salt and pepper.
Step 2:
In a large deep skillet or Dutch oven heat olive oil over medium high heat Add the chicken and sauté until browned and just cooked through about 5 6 minutes Remove chicken to a plate and set aside.
Step 3:
In the same pot add onion and bell pepper Sauté for 3 minutes until softened Add garlic and cook for 1 minute more.
Step 4:
Stir in the orzo smoked paprika remaining Cajun seasoning and cayenne pepper Toast the orzo for 1 minute stirring frequently.
Step 5:
Pour in the chicken broth heavy cream and milk Stir well scraping any browned bits from the bottom.
Step 6:
Bring to a gentle boil then reduce heat to medium low Cover and simmer for 10 12 minutes stirring occasionally until orzo is tender and most liquid is absorbed.
Step 7:
Return the chicken to the pot along with spinach (if using) Stir in Parmesan cheese until melted and creamy.
Step 8:
Taste and adjust seasoning If sauce is too thick add a splash more milk or broth.
Step 9:
Serve hot garnished with parsley and extra Parmesan.
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This recipe has brought many family dinners full of laughter and warmth.

Required Tools

Large deep skillet or Dutch oven with lid Cutting board and knife Wooden spoon or spatula Measuring cups and spoons Grater (for Parmesan)

Allergen Information

Contains Dairy (cream milk Parmesan) Wheat (orzo) Possible Celery (in broth) Check Cajun seasoning and broth labels for hidden allergens.

Nutritional Information

Calories: 570 Total Fat: 27 g Carbohydrates: 48 g Protein: 37 g

Enjoy a bowl of One-Pot Cajun Chicken Alfredo Orzo, a weeknight dinner with fragrant spices. Save
Enjoy a bowl of One-Pot Cajun Chicken Alfredo Orzo, a weeknight dinner with fragrant spices. | tazzsip.com

This dish is perfect for busy nights and will satisfy both spice lovers and comfort food seekers alike.

Recipe Guide

Can I substitute the chicken with other proteins?

Yes, shrimp or smoked sausage can be used instead of chicken to change the flavor profile while maintaining the creamy texture.

What can I use if I want a lighter option?

Half-and-half can replace the heavy cream to reduce richness while keeping the sauce creamy.

How can I add more vegetables to this dish?

Mushrooms or peas are great additions to increase the vegetable content and complement the flavors.

Is it necessary to toast the orzo before cooking?

Toasting the orzo enhances its nutty flavor and adds depth to the dish, though it can be skipped if short on time.

How do I prevent the sauce from becoming too thick?

If the sauce thickens too much, add a splash of milk or broth to loosen it to desired consistency.

One-Pot Cajun Chicken Alfredo

Tender chicken simmered with Cajun spices, creamy Alfredo sauce, and orzo for an easy, flavorful meal.

Setup duration
15 min
Heat duration
25 min
Complete duration
40 min
Created by Daniel Brooks

Classification Easy Weeknight Eats

Complexity Easy

Heritage American, Cajun-Inspired

Output 4 Portions

Nutrition specifications None specified

Components

Proteins

01 2 large boneless, skinless chicken breasts, cut into bite-sized pieces

Vegetables

01 1 small yellow onion, finely chopped
02 3 cloves garlic, minced
03 1 red bell pepper, diced
04 1 cup baby spinach, roughly chopped (optional)

Pantry

01 2 tablespoons olive oil
02 1 1/2 cups orzo pasta
03 2 1/2 cups low-sodium chicken broth
04 1 cup heavy cream
05 1/2 cup milk

Spices & Seasonings

01 1 tablespoon Cajun seasoning
02 1/2 teaspoon smoked paprika
03 1/2 teaspoon salt, or to taste
04 1/4 teaspoon freshly ground black pepper
05 Pinch of cayenne pepper (optional)

Cheeses

01 3/4 cup freshly grated Parmesan cheese

Garnish

01 Chopped fresh parsley
02 Extra Parmesan cheese

Method

Phase 01

Season chicken: Combine chicken pieces with half of the Cajun seasoning, salt, and black pepper; mix thoroughly.

Phase 02

Brown chicken: Heat olive oil in a large deep skillet or Dutch oven over medium-high heat; add chicken and sauté until browned and cooked through, approximately 5 to 6 minutes. Remove chicken and set aside.

Phase 03

Sauté vegetables: In the same pot, add onion and red bell pepper; cook for 3 minutes until softened. Add minced garlic and cook an additional 1 minute.

Phase 04

Toast orzo and spices: Stir in orzo pasta, smoked paprika, remaining Cajun seasoning, and cayenne pepper if using. Toast for 1 minute, stirring frequently.

Phase 05

Add liquids: Pour chicken broth, heavy cream, and milk into the pot; mix well, scraping up any browned bits from the bottom.

Phase 06

Simmer orzo: Bring mixture to a gentle boil, reduce heat to medium-low, cover, and simmer for 10 to 12 minutes. Stir occasionally until orzo becomes tender and most liquid is absorbed.

Phase 07

Combine chicken and spinach: Return cooked chicken to the pot. Add spinach if desired and stir in Parmesan cheese until fully melted and creamy.

Phase 08

Adjust seasoning: Taste and modify seasoning as needed. If sauce is too thick, add small amounts of milk or broth to reach preferred consistency.

Phase 09

Serve: Dish the creamy Cajun chicken Alfredo orzo into serving bowls and garnish with chopped parsley and extra Parmesan cheese.

Necessary tools

  • Large deep skillet or Dutch oven with lid
  • Cutting board and knife
  • Wooden spoon or spatula
  • Measuring cups and spoons
  • Grater for Parmesan cheese

Allergy details

Review ingredients carefully for potential allergens and seek professional medical guidance when uncertain.
  • Contains dairy and wheat (orzo). Possible celery allergen in chicken broth. Verify Cajun seasoning and broth labels for hidden allergens.

Dietary information (per portion)

Values shown are estimates only - consult healthcare providers for specific advice.
  • Energy: 570
  • Fats: 27 g
  • Carbohydrates: 48 g
  • Proteins: 37 g