Spinach Artichoke Grilled Cheese

Featured in: Quick Comfort Snacks

Transform classic grilled cheese into a gourmet sandwich with this spinach and artichoke masterpiece. Creamy filling combines sautéed spinach, tender artichoke hearts, mozzarella, cream cheese, and Parmesan between golden sourdough slices.

This 25-minute sandwich delivers restaurant-quality flavor at home. Buttered bread toasts to crispy perfection while cheese melts into a luxurious center. Perfect for vegetarian lunch or casual dinner, it pairs beautifully with tomato soup.

Updated on Sun, 18 Jan 2026 14:24:00 GMT
Golden-brown sourdough slices overflowing with creamy spinach artichoke grilled cheese filling, showcasing melted mozzarella on a rustic plate. Save
Golden-brown sourdough slices overflowing with creamy spinach artichoke grilled cheese filling, showcasing melted mozzarella on a rustic plate. | tazzsip.com

My neighbor knocked on the door one rainy Tuesday holding a jar of artichoke hearts she didn't want to waste. I had spinach wilting in the crisper and half a block of cream cheese calling my name. What started as improvisation turned into something I now crave on cold afternoons when I need comfort without the fuss. The crunch of sourdough against that creamy, tangy filling felt like discovering a secret handshake between two favorite foods.

I made this for my sister after her thesis defense, thinking she needed something more exciting than a regular grilled cheese. She took one bite and closed her eyes, which is her version of a standing ovation. We sat on the porch with our sandwiches cut into triangles, and she told me it tasted like celebration food disguised as comfort food. That's exactly what it is.

Ingredients

  • Shredded mozzarella cheese: This is your melt factor, the cheese that stretches and binds everything into gooey perfection without overpowering the other flavors.
  • Cream cheese, softened: It adds body and tang to the filling, making it spreadable and luscious instead of dry or crumbly.
  • Grated Parmesan cheese: A little sharpness goes a long way here, deepening the flavor and adding a subtle nuttiness.
  • Unsalted butter, softened: Spread it on the outside of the bread for that crisp, golden crust that crackles when you bite into it.
  • Fresh spinach, chopped: Wilting it first concentrates the flavor and removes excess water that would otherwise make your sandwich soggy.
  • Canned or jarred artichoke hearts, drained and chopped: These bring a tender, slightly tangy bite that makes the filling feel special and grown up.
  • Small garlic clove, minced: Just enough to whisper through the filling without shouting, adding warmth and depth.
  • Sourdough bread: The slight tang and sturdy structure hold up to the filling and crisp beautifully without falling apart.
  • Salt: Brings all the flavors into focus, especially important since spinach and artichokes can taste flat without it.
  • Freshly ground black pepper: Adds a gentle heat and complexity that wakes up the creamy elements.
  • Red pepper flakes (optional): A pinch gives just enough kick to keep things interesting without overwhelming the dish.

Instructions

Wilt the Spinach:
Add the spinach to a medium skillet over medium heat with just a splash of water. Let it collapse and soften for a minute or two, then drain it well, pressing out any moisture with the back of a spoon.
Mix the Filling:
In a bowl, combine the wilted spinach, chopped artichoke hearts, cream cheese, mozzarella, Parmesan, minced garlic, salt, pepper, and red pepper flakes if you like a little heat. Stir until everything is evenly blended and creamy.
Assemble the Sandwiches:
Spread the spinach-artichoke mixture generously onto two slices of sourdough, then top each with another slice to close the sandwiches. Press gently so they hold together.
Butter the Bread:
Spread softened butter on the outside of each sandwich, covering every corner so the bread crisps evenly. This step makes all the difference between pale and golden.
Grill Until Golden:
Heat a large nonstick skillet or griddle over medium heat and place the sandwiches in the pan. Cook for 3 to 4 minutes per side, pressing gently with a spatula, until the bread is crisp and deep golden and the cheese has melted into the filling.
Slice and Serve:
Remove the sandwiches from the heat, let them rest for a moment, then slice in half. Serve them while they're still warm and the cheese is stretchy.
A close-up view of crispy spinach artichoke grilled cheese, with vibrant green spinach and chopped artichoke peeking from the melted cheese. Save
A close-up view of crispy spinach artichoke grilled cheese, with vibrant green spinach and chopped artichoke peeking from the melted cheese. | tazzsip.com

One Saturday morning, I made these for brunch and paired them with tomato soup I'd simmered with basil from the windowsill. My friend dipped her sandwich into the soup and declared it the best thing she'd eaten all week. We sat at the kitchen table long after the plates were empty, talking and laughing, and I realized food like this doesn't just fill you up, it keeps you there.

Making It Your Own

If you want a little more herbaceousness, toss in a handful of fresh basil or a sprinkle of smoked paprika before you close the sandwiches. Whole wheat or multigrain bread works beautifully if you want a heartier, slightly nutty base. I've also swapped in provolone or fontina when I'm feeling adventurous, and both brought their own quiet magic to the mix.

What to Serve Alongside

This sandwich begs for tomato soup, the kind that's silky and just a little sweet, perfect for dunking. A simple green salad with lemon vinaigrette balances the richness, or you can keep it casual with pickle spears and kettle chips. On nights when I'm extra hungry, I'll add a handful of roasted vegetables on the side.

Storing and Reheating

Leftovers can be wrapped in foil and stored in the fridge for up to two days, though the bread won't stay as crisp. Reheat them in a skillet over low heat, pressing gently, to bring back some of that crunch and melt the cheese again.

  • Don't microwave them or the bread will turn rubbery and sad.
  • You can make the filling ahead and store it in the fridge for up to three days, then assemble and grill fresh.
  • If you're doubling the recipe, keep finished sandwiches warm in a low oven while you cook the rest.
Perfectly grilled sourdough halves revealing the gooey, savory spinach artichoke grilled cheese interior, ideal for a comforting lunch. Save
Perfectly grilled sourdough halves revealing the gooey, savory spinach artichoke grilled cheese interior, ideal for a comforting lunch. | tazzsip.com

This sandwich has become my answer to grey days, surprise guests, and nights when I need something cozy without much effort. I hope it finds a place in your kitchen the way it has in mine.

Recipe Guide

Can I prepare the filling ahead of time?

Yes, you can make the spinach-artichoke filling up to 2 days ahead. Store it in an airtight container in the refrigerator. Assemble and cook the sandwiches fresh for best results.

What bread works best for this sandwich?

Sourdough provides tanginess and structural integrity. Alternatives include whole wheat, multigrain, or brioche. Choose bread with enough substance to contain the creamy filling without becoming soggy.

How do I prevent the sandwich from being too greasy?

Use moderate butter on the exterior—just enough for golden browning. Drain the sautéed spinach thoroughly to remove excess moisture. Cook over medium heat rather than high to prevent butter from burning.

Can I add protein to make it heartier?

Absolutely. Consider adding crumbled feta, crispy bacon, sliced tomatoes, or sautéed mushrooms. Keep proportions balanced so the bread can still seal and cook evenly.

What's the best way to melt the cheese completely?

Cook over medium heat for 3-4 minutes per side, pressing gently with a spatula. Covering the skillet with a lid for the last minute of cooking traps heat and melts cheese faster without burning the bread.

How do I reheat leftovers?

Reheat in a skillet over medium-low heat for 2-3 minutes per side, or wrap loosely in foil and warm in a 350°F oven for 5-7 minutes. Avoid microwaving, which can make the bread soggy.

Spinach Artichoke Grilled Cheese

Gourmet grilled cheese with creamy spinach and artichoke filling, melted mozzarella, and golden sourdough. Quick and satisfying.

Setup duration
15 min
Heat duration
10 min
Complete duration
25 min
Created by Daniel Brooks

Classification Quick Comfort Snacks

Complexity Easy

Heritage American

Output 2 Portions

Nutrition specifications Meat-free

Components

Dairy

01 1 cup shredded mozzarella cheese
02 1/2 cup cream cheese, softened
03 1/4 cup grated Parmesan cheese
04 2 tablespoons unsalted butter, softened

Vegetables

01 1 cup fresh spinach, chopped
02 1/2 cup canned artichoke hearts, drained and chopped
03 1 small garlic clove, minced

Bread

01 4 slices sourdough bread

Seasonings

01 1/4 teaspoon salt
02 1/8 teaspoon freshly ground black pepper
03 Pinch of red pepper flakes, optional

Method

Phase 01

Prepare the spinach: In a medium skillet over medium heat, add spinach with a splash of water. Sauté for 1 to 2 minutes until wilted, then drain excess moisture.

Phase 02

Combine filling ingredients: In a bowl, combine sautéed spinach, chopped artichoke hearts, cream cheese, mozzarella, Parmesan, minced garlic, salt, pepper, and red pepper flakes if using. Mix until well blended.

Phase 03

Assemble sandwiches: Spread the spinach-artichoke mixture evenly onto two slices of sourdough bread. Top with the remaining bread slices to form sandwiches.

Phase 04

Butter the exterior: Butter the outside surfaces of all bread slices thoroughly.

Phase 05

Cook the sandwiches: Heat a large nonstick skillet or griddle over medium heat. Place sandwiches in the skillet and cook for 3 to 4 minutes per side, pressing gently, until bread is golden brown and cheese is melted.

Phase 06

Finish and serve: Remove from heat, slice diagonally in half, and serve immediately while hot.

Necessary tools

  • Medium skillet
  • Mixing bowl
  • Spatula
  • Nonstick skillet or griddle
  • Knife

Allergy details

Review ingredients carefully for potential allergens and seek professional medical guidance when uncertain.
  • Contains milk from cheese and butter
  • Contains wheat from sourdough bread
  • May contain traces of soy or tree nuts depending on bread and cheese brand sourcing

Dietary information (per portion)

Values shown are estimates only - consult healthcare providers for specific advice.
  • Energy: 430
  • Fats: 24 g
  • Carbohydrates: 39 g
  • Proteins: 16 g